NRG-GY022: Assessment of Carboplatin Clearance Predictors: A PK Study on NCI-sponsored Clinical Trials or Standard of Care Treatments Using Carboplatin. Activation reminder – This study opened to accrual on November 18, 2019. Please note: This study is not limited to Gyn patients but rather any patients who are being treated with carboplatin. (Posted on CTSU)
GYNECOLOGIC GOG-0279: Reminder – Closure to accrual effective February 20, 2020 at 5pm ET (posted on NRG Oncology)
NRG-GI004: Amendment 4; version date: October 7, 2019 (posted on CTSU)
NRG-GY006: Amendment 5; version date: November 25, 2019 (posted on CTSU)
OTHER PROTOCOL NOTICES
NRG-BR003: Memo re: Blood Sample Collections for ctDNA (posted on CTSU)
NRG-GY004: UPDATED memo - Notification of Signature Requirement (posted on CTSU)
NRG-GY005: Updated contact information for Data Management (posted on CTSU)
NRG-GY005: CEC Whole Blood Shipping Address (posted on CTSU)
NRG-GY009: Updated contact information for Data Management (posted on CTSU)
NRG-GY009: Block Submission Reminder memo (posted on CTSU)
3. LUNG NRG-LU006: A Participant Brochure is available on the CTSU website (CIRB Documents > Amendment Reviews > Support Documents > #1)
4. NRG Biospecimen Bank - Columbus
Form TR for Biospecimens Shipped to NRG Biospecimen Bank-Columbus Read more
Biospecimen Bank-Columbus & SDMC Undergoing Refurbishment Read more
5. DMC Minutes
The January 2020 DMC meeting minutes are now available on the CTSU and NRG Oncology websites.
6. VTOC TRAINING
The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, and NRG-CC004. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, March 11, 2020.
DRUG SAFETY UPDATES
Safety updates have been issued for the following studies:
NRG Oncology Trial Shows Hippocampal Avoidance During Whole-Brain Radiotherapy for Brain Metastases Reduces Risks of Cognitive Toxicity and Neurologic Symptoms
Results from the NRG Oncology clinical study NRG-CC001 concluded that lowering radiotherapy dose to hippocampal stem cells improves cognitive and patient-reported outcomes for patients with brain metastases. These findings were presented at Plenary Sessions at the 2018 Society for Neuro-Oncology (SNO) and the 2019 American Academy of Neurology (AAN) Annual Meetings and are now published in the
Journal of Clinical Oncology. Read more
NRG NCORP solicits PILOT projects addressing Cancer Prevention and Control (CPC) priorities NRG Oncology NCORP is soliciting PILOT projects for applications focused on NRG NCORP Cancer Prevention and Control (CPC)priorities that will provide data that will directly lead to future Phase II-III CPC concepts. As put forward in our core grant, CPC priorities for funding include cancer prevention research and cancer control investigation aimed at understanding and/or ameliorating the symptoms and toxicity related to:
Gender-specific symptom reduction
Treatment dose alterations or delivery
Cancer risk reduction
Chemotherapy-induced peripheral neuropathy
Integral to these priorities, are the establishment of biospecimen repositories for molecular studies, as well as applications addressing/prioritizing health disparities, the elderly, racial and ethnic minorities, sexual and gender minorities, and rural residents.
Today, February 17, 2020 – The legacy NSABP Coordinator Online website will be unavailable due to scheduled maintenance. The planned outage is from 8am EST to 1pm EST. During this period, needed infrastructure upgrades will be implemented that are necessary to ensure the continued security and availability of the site. One effect of these upgrades will be that all users will be required to reset their account passwords on the next login attempt. User IDs are not changing, only the password will need to be reset. If you have questions or issues, please contact email@example.com.
Ship Batched Banked Specimens to NRGBB-UCSF prior to March 11, 2020
The NRG Oncology Biospecimen Bank San Francisco (UCSF) is requesting all sites to ship any stored/batch frozen specimens that are to be shipped to the SF bank from their -80C freezers to UCSF by March 11, 2020. ONLY ship specimens to SF from trials that are supposed to be banked at the UCSF location. Do NOT ship samples to UCSF if they are supposed to go to Columbus, Pittsburgh, or Baylor sites. The prepaid dry ice shipping labels addressed to UCSF will no longer be valid after March 31, 2020. New labels will be required after that date. Only ship Monday-Wednesday for these dry ice shipments. Please contact the bank at NRGBB@ucsf.edu with any questions.
These shipments should be sent to:
NRG Oncology Biospecimen Bank
2340 Sutter St, Rm S341
San Francisco, CA 94115
Phone: 415-476-7864 (lab)
REMINDER: President's Day Holiday Closures The NRG Oncology Philadelphia East Operations Center, Buffalo SDMC, and San Francisco Biospecimen Bank locations will be closed for the President's Day holiday today, Monday, February 17, 2020, and will resume operations on the next business day. All other NRG Oncology offices and bank locations will be open during regular business hours on President's Day.
NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.
Crook J, Rodgers J, Pisansky TM, Trabulsi EJ, Amin MB, Bice W, Morton GC, Pervez N, Vigneault E, Catton CN, Michalski JM, Roach M III, Beyer DC, Rossi PJ, Horwitz E, Donavanik V, Sandler HM. Clinical Outcomes For Locally Recurrent Prostate Adenocarcinoma Patients Receiving Transperineal Ultrasound-Guided Brachytherapy Following External Beam Radiotherapy. ABS (American Brachytherapy Society). World Congress of Brachytherapy, Vienna, Austria 4/2/2020
Please note the following upcoming meeting and abstract submission deadline dates